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        8-Hydroxyquinoline

        8-Hydroxyquinoline
        8-Hydroxyquinoline structure
        CAS No.
        148-24-3
        Chemical Name:
        8-Hydroxyquinoline
        Synonyms
        OQ;8-OQ;Oxin;Tumex;OXINE;8-Oxine;BIOQUIN;NSC 2039;8-Quinol;Fennosan
        CBNumber:
        CB8435187
        Molecular Formula:
        C9H7NO
        Formula Weight:
        145.16
        MOL File:
        148-24-3.mol

        8-Hydroxyquinoline Properties

        Melting point:
        70-73 °C(lit.)
        Boiling point:
        267 °C752 mm Hg(lit.)
        Density 
        1.0340
        refractive index 
        1.4500 (estimate)
        Flash point:
        267°C
        storage temp. 
        Store at RT.
        solubility 
        0.56g/l
        form 
        Liquid
        pka
        5.017(at 20℃)
        color 
        White to pale yellow or light beige
        Water Solubility 
        INSOLUBLE
        Sensitive 
        Light Sensitive
        Merck 
        14,4843
        BRN 
        114512
        InChIKey
        MCJGNVYPOGVAJF-UHFFFAOYSA-N
        CAS DataBase Reference
        148-24-3(CAS DataBase Reference)
        EWG's Food Scores
        1-3
        NIST Chemistry Reference
        8-Quinolinol(148-24-3)
        EPA Substance Registry System
        8-Quinolinol (148-24-3)
        SAFETY
        • Risk and Safety Statements
        Symbol(GHS) 
        GHS07,GHS08
        Signal word  Warning
        Hazard statements  H302-H341
        Precautionary statements  P201-P280-P301+P312a-P308+P313-P405-P501a
        Hazard Codes  Xn,Xi
        Risk Statements  22-68-36/37/38
        Safety Statements  45-36/37/39-26-36
        RIDADR  2811
        WGK Germany  3
        RTECS  VC4200000
        Hazard Note  Harmful/Irritant
        TSCA  Yes
        HazardClass  9
        PackingGroup  III
        HS Code  29334990
        Toxicity LD50 orally in Rabbit: 1200 mg/kg
        NFPA 704
        1
        2 0

        8-Hydroxyquinoline price More Price(21)

        Manufacturer Product number Product description CAS number Packaging Price Updated Buy
        Sigma-Aldrich 252565 8-Hydroxyquinoline ACS reagent, 99% 148-24-3 50g $58.2 2019-12-02 Buy
        Sigma-Aldrich 252565 8-Hydroxyquinoline ACS reagent, 99% 148-24-3 1kg $284 2019-12-02 Buy
        TCI Chemical H0305 8-Quinolinol >99.0%(GC)(T) 148-24-3 25g $18 2019-12-02 Buy
        TCI Chemical H0305 8-Quinolinol >99.0%(GC)(T) 148-24-3 500g $87 2019-12-02 Buy
        Alfa Aesar 041272 8-Hydroxyquinoline, ACS 148-24-3 50g $33.2 2019-12-02 Buy

        8-Hydroxyquinoline Chemical Properties,Uses,Production

        Chemical Properties

        Cream-colored crystals

        Uses

        antiinfectant, complexing agent

        Definition

        ChEBI: A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.

        brand name

        Aci-jel;Benzease;Chinosol;Cp-cap;Dermacid;Dermoplast;Fennosan h 30;Heriat;Hydroxybenoxopyridine;Medicone derma-hc;Oxykin;Oxyquinoline-rhp;Pedivol;Phenopyridine;Preconsol;Quinoderm;Quinoped;Quinophenol;Recta medicone-hc;Semori;Serohinol;Serorhinol;Superol;Trimo-san;Triva douch powder;Triva jel.

        World Health Organization (WHO)

        Halogenated hydroxyquinoline is structurally related to clioquinol. See WHO comment for clioquinol. (Reference: (WHODI) WHO Drug Information, 77.1, 9, 1977)

        General Description

        White to off-white or faintly yellow crystalline powder. Phenolic odor.

        Air & Water Reactions

        Insoluble in water.

        Reactivity Profile

        8-Hydroxyquinoline darkens on exposure to light. 8-Hydroxyquinoline readily forms stable metal chelates. 8-Hydroxyquinoline is incompatible with strong oxidizers. 8-Hydroxyquinoline is also incompatible with many metal ions.

        Hazard

        Toxic by ingestion. Questionable carcinogen.

        Fire Hazard

        Flash point data for 8-Hydroxyquinoline are not available; however, 8-Hydroxyquinoline is probably combustible.

        Clinical Use

        Oxine, quinophenol, or oxyquinoline is the parent compoundfrom which the antiprotozoal oxyquinolines havebeen derived. The antibacterial and antifungal properties of oxine and its derivatives, which are believed to result fromthe ability to chelate metal ions, are well known. Aqueoussolutions of acid salts of oxine, particularly the sulfate(Chinosol, Quinosol), in concentrations of 1:3,000 to1:1,000, have been used as topical antiseptics. The substitutionof an iodine atom at the 7-position of 8-hydroxyquinolinesyields compounds with broad-spectrum amebicidalproperties.

        Safety Profile

        Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Experimental reproductive effects. A central nervous system stimulant. Human mutation data reported. Combustible when exposed to heat or flame. When heated to decomposition it emits hghly toxic fumes of NOx.

        Purification Methods

        Crystallise oxine from hot EtOH, acetone, pet ether (b 60-80o) or water. Crude oxine can be purified by precipitation of copper oxinate, followed by liberation of free oxine with H2S or by steam distillation after acidification with H2SO4. Store it in the dark. It forms complexes with many metals. [Manske et al. Can J Research 27F 359 1949, Phillips Chem Rev 56 271 1956, Beilstein 21 III/IV 1135, 21/3 V 252.]

        8-Hydroxyquinoline Preparation Products And Raw materials

        Raw materials

        Preparation Products


        8-Hydroxyquinoline Suppliers

        Global( 595)Suppliers
        Supplier Tel Fax Email Country ProdList Advantage
        Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 0536-2101172-
        sdfantai@163.com China 504 58
        Alfa Aesar 400-610-6006; 021-67582000
        021-67582001/03/05 saleschina@alfa-asia.com China 30163 84
        Tangshan Moneide Trading Co., Ltd. 0315-8309571
        +86-315-7726572 sales@moneidechem.com China 685 57
        CHMA Chemical Technology (Shanghai) Co., Ltd 021-61556450 15800904410
        021-61556450 sales@chmachem.com China 2840 58
        Shanghai Pengsuo Biochemical Technology Co., Ltd. 021-59118555
        021-59119222 pengsuochem@163.com China 3680 55
        Hubei Yuancheng Saichuang Technology Co., Ltd. 18062666868/13048470578 QQ2355779403/2355880551
        023-60363599,027-68886696 andy@ycgmp.com,2355880551@qq.com,2355779403@qq.com China 5053 58
        Suzhou Nuowo Kang Chemical Co., Ltd.
        0512-68228771 sznwk15@126.com;sznwk15@126.com China 34 58
        Shouguang Jiasheng Chemical Co., Ltd. 0536-7971999- ;0536-7971999
        0536-7971999 sgjiasheng@hotmail.com;sgjiasheng@hotmail.com; China 247 58
        Changzhou Share Chemical Co., Ltd 0519-82619998
        +86-519-82619997 wu@sharechem.com China 54 54
        J & K SCIENTIFIC LTD. 010-82848833- ;010-82848833-
        86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

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        View Lastest Price from 8-Hydroxyquinoline manufacturers

        Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
        2018-08-06 8-Hydroxyquinoline
        148-24-3
        US $1.00 / KG 1KG 99% 1 career henan chemical co

        8-Hydroxyquinoline Spectrum


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