老彩票app下载

<address id="gUwjA"></address><datalist id="gUwjA"><strike id="gUwjA"></strike></datalist>
    <param id="gUwjA"><progress id="gUwjA"><figcaption id="gUwjA"></figcaption></progress></param>

    <figcaption id="gUwjA"><section id="gUwjA"><area id="gUwjA"><address id="gUwjA"></address><i id="gUwjA"></i><nav id="gUwjA"></nav></area><rp id="gUwjA"></rp><bdo id="gUwjA"><dl id="gUwjA"><sub id="gUwjA"></sub></dl></bdo></section><figcaption id="gUwjA"></figcaption></figcaption>

      • <bdo id="gUwjA"></bdo><span id="gUwjA"><td id="gUwjA"></td></span><rp id="gUwjA"></rp>
        ChemicalBook
        Chinese Japanese Germany Korea

        Butylated Hydroxytoluene

        Chemical Properties Mammalian physiology
        Butylated Hydroxytoluene
        Butylated Hydroxytoluene structure
        CAS No.
        128-37-0
        Chemical Name:
        Butylated Hydroxytoluene
        Synonyms
        p21;BHT;ao4k;ao29;BUKS;SDI1;cao1;cao3;DBMP;P 21
        CBNumber:
        CB8355755
        Molecular Formula:
        C15H24O
        Formula Weight:
        220.35
        MOL File:
        128-37-0.mol

        Butylated Hydroxytoluene Properties

        Melting point:
        69-73 °C(lit.)
        Boiling point:
        265 °C(lit.)
        Density 
        1.048
        vapor density 
        7.6 (vs air)
        vapor pressure 
        <0.01 mm Hg ( 20 °C)
        FEMA 
        2184 | BUTYLATED HYDROXYTOLUENE
        refractive index 
        1.4859
        Flash point:
        127 °C
        storage temp. 
        0-6°C
        solubility 
        methanol: 0.1 g/mL, clear, colorless
        pka
        pKa 14(H2O t = 25 c = 0.002 to 0.01) (Uncertain)
        form 
        Crystals
        color 
        white
        Odor
        faint characteristic odor
        Water Solubility 
        insoluble
        Merck 
        14,1548
        BRN 
        1911640
        Stability:
        Stable, but light-sensitive. Incompatible with acid chlorides, acid anhydrides, brass, copper, copper alloys, steel, bases, oxidizing agents. Combustible.
        InChIKey
        NLZUEZXRPGMBCV-UHFFFAOYSA-N
        CAS DataBase Reference
        128-37-0(CAS DataBase Reference)
        EWG's Food Scores
        4
        NIST Chemistry Reference
        Butylated hydroxytoluene(128-37-0)
        EPA Substance Registry System
        2,6-Di-tert-butyl-p-cresol (128-37-0)
        SAFETY
        • Risk and Safety Statements
        Symbol(GHS) 
        GHS09,GHS07,GHS08
        Signal word  Warning
        Hazard statements  H302-H315-H317-H319-H370-H373-H401-H411-H410
        Precautionary statements  P273-P501-P305+P351+P338-P260-P264-P270-P272-P280-P301+P312+P330-P302+P352+P333+P313+P363-P305+P351+P338+P337+P313-P307+P311-P391-P405
        Hazard Codes  Xn,N
        Risk Statements  22-36/37/38-36/38-50/53
        Safety Statements  26-36-37/39-61-60
        RIDADR  3077
        WGK Germany  1
        RTECS  GO7875000
        8-10-23
        Autoignition Temperature 878 °F
        TSCA  Yes
        HazardClass  9
        PackingGroup  III
        HS Code  29071900
        Toxicity LD50 orally in mice: 1040 mg/kg (McOmie)
        NFPA 704
        1
        0 0

        Butylated Hydroxytoluene price More Price(29)

        Manufacturer Product number Product description CAS number Packaging Price Updated Buy
        Sigma-Aldrich 03762 2,6-Di-tert-butyl-4-methylphenol tested according to Ph.Eur. 128-37-0 500g $36.3 2019-12-02 Buy
        Sigma-Aldrich 1082708 Butylated hydroxytoluene United States Pharmacopeia (USP) Reference Standard 128-37-0 500mg $399.35 2019-12-02 Buy
        TCI Chemical D0228 2,6-Di-tert-butyl-p-cresol >99.0%(GC) 128-37-0 25g $18 2019-12-02 Buy
        TCI Chemical D0228 2,6-Di-tert-butyl-p-cresol >99.0%(GC) 128-37-0 500g $33 2019-12-02 Buy
        Alfa Aesar A16863 2,6-Di-tert-butyl-4-methylphenol, 99% 128-37-0 250g $24.7 2019-12-02 Buy

        Butylated Hydroxytoluene Chemical Properties,Uses,Production

        Chemical Properties

        Butylated hydroxytoluene(BHT) is white or light yellow crystal. BHT has a melting point of 71°C, a boiling point of 265°C, a relative density of 1.048 (20/4°C), and a refractive index of 1.4859 (75°C). Solubility of BHT at normal temperature: methanol 25, ethanol 25-26, isopropanol 30, mineral oil 30, acetone 40, petroleum ether 50, benzene 40, lard (40-50°C ) 40-50, corn oil and soybean oil 40-50. BHT is insoluble in water, 10NaOH solution, glycerol, and propylene glycol. BHT is odorless, odorless with good thermal stability.

        Mammalian physiology

        BHT is a phenolic antioxidant. BHT can inhibit lipid peroxidation and cause lung injury in mice and promote tumor growth, which may be due to the metabolites of BHT, 6-tert-butyl-2-[2′-(2′-hydroxymethyl)-propyl]-4-Methylphenol. BHT metabolites have also been reported to cause DNA strand breaks in cultured cells and DNA breaks between nucleosomes (a typical feature of apoptosis). A single intraperitoneal injection of BHT (60mg/kg body weight) into rats caused a significant increase in nuclear DNA methyltransferase activity in the liver, kidney, heart, spleen, brain, and lung.

        Chemical Properties

        BHA and BHT (butylated hydroxytoluene) are monohydric phenolic antioxidants that, prior to their introduction and acceptance in the food industry, were used to protect petroleum against oxidative degumming. BHT has a very faint, musty, occasional cresylictype odor. BHA and BHT are extensively used in foods as antioxidants. Most fats, oils and fat-containing foods are naturally susceptible to rapid rancification and other oxidative reactions that produce compounds having objectionable taste and odor, making foods containing them unpalatable. Lipid oxidation is autocatalytic and proceeds as a complex of chain reactions, the nature and speed of which vary with the substrate, temperature, light, availability of oxygen and presence or absence of oxidation catalysts. Antioxidants like BHT act as “chain breaks” in the autooxidation processes under the usual conditions of processing, storage and use of fat-containing foods (Burdock, 1997).

        Chemical Properties

        white crystalline solid

        Chemical Properties

        BHT is a white to pale yellow crystalline solid or powder.

        Chemical Properties

        Butylated hydroxytoluene occurs as a white or pale yellow crystalline solid or powder with a faint characteristic phenolic odor.

        Occurrence

        Not reported found naturally.

        Uses

        Because they prevent rancidity, antioxidants are of great interest to the food industry. For example, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), and EDTA are frequently used to preserve various foods, such as cheese or fried products. Butylated hydroxytoluene is a powerful inhibitor of lipid peroxidation, yet large doses of it can induce oxidative DNA damage and cancer development in the rat forestomach.

        Uses

        BHT is also known as butylated hydroxy toluene. It is an anti-oxidant that also has preservative and masking capabilities.

        Uses

        Butylated Hydroxytoluene (BHT) is an antioxidant that functions similarly to butylated hydroxyanisole (BHA) but is less stable at high temperatures. It is also termed 2,6-di-tert-butyl-para-cresol. See Butylated Hydroxyanisole.

        Uses

        Antioxidant 264 as general antioxidants is used widely in polymer materials, petroleum products and food processing industries. Antioxidant 264 is commonly used rubber antioxidant, heat, oxygen aging have some protective effect, but also can inhibit copper harm. This product does not change color, not pollution. Antioxidants 264 high solubility in oil, no precipitation, less volatile, non-toxic and non-corrosive.

        Uses

        Antioxidant for food, animal feed, petroleum products, synthetic rubbers, plastics, animal and vegetable oils, soaps. Antiskinning agent in paints and inks.

        Definition

        ChEBI: A member of the class of phenols that is 4-methylphenol substituted by tert-butyl groups at positions 2 and 6.

        Preparation

        BHT is produced commercially by the alkylation of para-cresol with isobutylene. BHT is also produced by several western European manufacturers, production/processing plants in Germany, France, the Netherlands, United Kingdom and Spain.

        Production Methods

        Prepared by the reaction of p-cresol with isobutene.

        General Description

        White crystalline solid.

        Air & Water Reactions

        Insoluble in water.

        Reactivity Profile

        Phenols, such as 2,6-Di-tert-butyl-4-methylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Many of them form metal salts that tend toward detonation by rather mild shock. May react with oxidizing materials.

        Fire Hazard

        2,6-Di-tert-butyl-4-methylphenol is combustible.

        Pharmaceutical Applications

        Butylated hydroxytoluene is used as an antioxidant in cosmetics, foods, and pharmaceuticals. It is mainly used to delay or prevent the oxidative rancidity of fats and oils and to prevent loss of activity of oil-soluble vitamins.
        Butylated hydroxytoluene is also used at 0.5–1.0% w/w concentration in natural or synthetic rubber to provide enhanced color stability.
        Butylated hydroxytoluene has some antiviral activity and has been used therapeutically to treat herpes simplex labialis.

        Contact allergens

        This antioxidant is contained in food, adhesive glues, industrial oils, and greases, including cutting fluids. Sensitization seems very rare.

        Safety Profile

        Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion. Anexperimental teratogen. Other experimental reproductiveeffects. A human skin irritant. A skin and eye irritant.Questionable carcinogen with experimental carcinogenicand

        Safety

        Butylated hydroxytoluene is readily absorbed from the gastrointestinal tract and is metabolized and excreted in the urine mainly as glucuronide conjugates of oxidation products. Although there have been some isolated reports of adverse skin reactions, butylated hydroxytoluene is generally regarded as nonirritant and nonsensitizing at the levels employed as an antioxidant.
        The WHO has set a temporary estimated acceptable daily intake for butylated hydroxytoluene at up to 125 μg/kg body-weight.
        Ingestion of 4 g of butylated hydroxytoluene, although causing severe nausea and vomiting, has been reported to be nonfatal.
        LD50 (guinea pig, oral): 10.7 g/kg
        LD50 (mouse, IP): 0.14 g/kg
        LD50 (mouse, IV): 0.18 g/kg
        LD50 (mouse, oral): 0.65 g/kg
        LD50 (rat, oral): 0.89 g/kg

        Potential Exposure

        DBPC is used as a food and feed additive, flavor, and packaging material; as an antioxidant in human foods and animal feeds. It is also used as an antioxidant to sta- bilize petroleum fuels, rubber and vinyl plastics.

        storage

        Exposure to light, moisture, and heat causes discoloration and a loss of activity. Butylated hydroxytoluene should be stored in a wellclosed container, protected from light, in a cool, dry place.

        Shipping

        UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

        Purification Methods

        Dissolve BHT in n-hexane at room temperature, then cool with rapid stirring, to -60o. The precipitate is separated, redissolved in hexane, and the process is repeated until the mother liquor is no longer coloured. The final product is stored under N2 at 0o [Blanchard J Am Chem Soc 82 2014 1960]. It has also been recrystallised from EtOH, MeOH, *benzene, n-hexane, methylcyclohexane or pet ether (b 60-80o), and is dried in a vacuum. [Beilstein 6 IV 3511.]

        Incompatibilities

        Butylated hydroxytoluene is phenolic and undergoes reactions characteristic of phenols. It is incompatible with strong oxidizing agents such as peroxides and permanganates. Contact with oxidizing agents may cause spontaneous combustion. Iron salts cause discoloration with loss of activity. Heating with catalytic amounts of acids causes rapid decomposition with the release of the flammable gas isobutene.

        Incompatibilities

        Contact with oxidizers may cause fire and explosion hazard.

        Regulatory Status

        GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (IM and IV injections, nasal sprays, oral capsules and tablets, rectal, topical, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

        Butylated Hydroxytoluene Preparation Products And Raw materials

        Raw materials

        Preparation Products


        Butylated Hydroxytoluene Suppliers

        Global( 602)Suppliers
        Supplier Tel Fax Email Country ProdList Advantage
        Shandong BothWin New Materials Co., Ltd. 0530-6681988
        78506549@qq.com CHINA 1 58
        Nanjing Datang Chemical Co., Ltd +86-25-85431992
        +86-25-85287178 vip@chemdatang.com China 72 66
        Spectrum Chemical Manufacturing Corp. 021-67601398-809
        021-57711696 marketing_china@spectrumchemical.com; China 9688 60
        Wuxi QianFeng Chemical Technology Co., Ltd. 0510-82860650-
        0510-82025215 qfhg@qianfengchem.com; China 40 55
        Sigma-Aldrich 021-61415566
        orderCN@merckgroup.com;orderCN@merckgroup.com China 34131 80
        Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
        021-50323701 sale@aladdin-e.com China 24984 65
        Nanjing FNAT Chemical Co.,Ltd. +86-25-86442672 13451895519
        +86-25-86442672 amywang@fnatchem.com China 69 58
        Shanghai BaiShun Biological Technology Co., Ltd 021-37581181
        021-57456066 sales@chem-mall.com China 10346 58
        Powerful Chemical (Shanghai) Co., Ltd. 021-62211590-
        021-54339019 pwfchem@163.com; China 47 58
        Hubei Hongjing Chemical Co., Ltd. 13669024603
        027-82333386 hb_hjhg@163.com China 133 58

        Related articles


        View Lastest Price from Butylated Hydroxytoluene manufacturers

        Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
        2019-04-05 Butylated Hydroxytoluene 2,6-Di-tert-butyl-4-methylphenol
        128-37-0
        US $1.00 / kg 1kg 99% High quality Factory Chemwill Asia Co.,Ltd.
        2019-04-02 Butylated hydroxytoluene Manufacturer; In stock GMP Factory
        128-37-0
        US $1.00 / KG 1KG High quality manufacturer TOP 3 largest production factory in China Chemwill Asia Co.,Ltd.
        2020-01-07 Butylated Hydroxytoluene
        28-37-0
        US $2.00 / KG 1KG 98% 100g , 1kg, 5kg , 50kg Career Henan Chemical Co

        Butylated Hydroxytoluene Spectrum


        128-37-0(Butylated Hydroxytoluene)Related Search:


        Copyright 2017 © ChemicalBook. All rights reserved
        <address id="gUwjA"></address><datalist id="gUwjA"><strike id="gUwjA"></strike></datalist>
        <param id="gUwjA"><progress id="gUwjA"><figcaption id="gUwjA"></figcaption></progress></param>

        <figcaption id="gUwjA"><section id="gUwjA"><area id="gUwjA"><address id="gUwjA"></address><i id="gUwjA"></i><nav id="gUwjA"></nav></area><rp id="gUwjA"></rp><bdo id="gUwjA"><dl id="gUwjA"><sub id="gUwjA"></sub></dl></bdo></section><figcaption id="gUwjA"></figcaption></figcaption>

          • <bdo id="gUwjA"></bdo><span id="gUwjA"><td id="gUwjA"></td></span><rp id="gUwjA"></rp>