LD50 in male, female rats, male, female mice (mg/kg): 981, 1051, 1299, 946 orally; in rats (mg/kg): >2000 dermally; LC50 in rats (mg/m3): >3450 by inhalation; LC50 (48 hr) in carp, rainbow trout, bluegill sunfish (ppm): 16.9, 4.0, 12.0 (Takenaka, 1990)
Pefurazoate Chemical Properties,Uses,Production
Pefurazoate is used to control seed-borne fungal diseases, particularly
Fusuriurn monuliniforme (Bakanae disease), Pyriculuriu ovyzae (rice
blast) and Cuchliobolus rniyubeunus (brown spot) on rice plants. It also
controls rice seedling blight caused by soil-borne pathogens (Trichoderme
viride and Fusurium spp.) in nursery box cultivation, and other fungal
pathogens on seeds of wheat, barley and flower bulbs.
Moderately toxic by ingestion, inhalation, and skin contact routes. Experimental reproductive effects.
Pefurazoate is readily degraded in soils, plants and mammals and the
molecule is susceptible to attack by enzymes at several sites. Metabolic
cleavage of the molecule gives simpler fragments formed by loss of the
Pefurazoate is stable in acidic media and slightly unstable in alkaline
media. It is stable to sunlight and decomposes only to the extent of about
1% after 90 days at 40 °C.
Pefurazoate Preparation Products And Raw materials